I just started playing through my first training camp game actually playing the game out calling plays and whatnot. Is there a way to make in game substitutions inside of the play by play of a game or does that all need to be controlled via depth charts before you start playing through the game? It's just training camp so not a big deal either way currently but want to be better prepared when the games start mattering.

The AI handles subs based on your packages and depth charts.