One of my players broke his arm and is out for 47 days. I went into the Depth Chart and gave all of his minutes to other players, but when I try to sim the game I get an error saying that I have an Invalid Roster Setting because one of my players is injured. Not sure what else I can do. I'm 22 games into my 1st season and right in the middle of league play. Any suggestions?

Did you move him DOWN out of the starting 5 in the Depth Chart?

Yeah I’m guessing that will be your fix. Outside of that you could have the AI update everything for your depth chart...that may fix whatever is off