In PF 21 version when looking at QB rushing stats some of them would end up with -300 yards at the end of the season. Has this been fixed in PF 22 ?

I thought we fixed that in one of the patches for PF21 too, but regardless it's fixed in PF22. We're still tuning though, so stats may vary from build to build until we get closer to release.

The AI still seem to struggle with calling QB running plays with dual threat QB’s. it could be just the playbook they are creating but it seem like majority of the rushing yardage from QB are from runs that ended up going for +50 yards.